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Born in Naples, the daughter of a doctor and a teacher, Dell'Anna grew up between Castel Volturno and Giugliano in Campania. She studied at the Drama Studio London and the Guildhall School of Music and Drama. After some minor roles, Dell'Anna had her breakout in 2012, when she played the twins Micaela e Manuela Cirillo in the Rai 3 soap opera Un posto al sole. In 2015 she landed her best known role, Patrizia Santore in the crime series Gomorrah. For her performance in Mario Martone's The King of Laughter, she got a David di Donatello nomination for Best Supporting Actress. She plays the lead role of Mother Cabrini in the 2024 film Cabrini, getting more exposure to English-speaking audiences.

A Taste for Murder
as PI Lara Sarrancino

Three Infallible Rules
as Claudia

C'è un posto nel mondo
as Anna Santi

My Family
as Maria

La coda del diavolo
as Fabiana Lai

A Dark Story
as PM

Cabrini
as Francesca Cabrini

Mixed by Erry
as Marisa Frattasio

Flowing
as Cristina

Toscana
as Sophia

The Hand of God
as Sorella Armando

The King of Laughter
as Luisa De Filippo

Tensione superficiale
as Michela

Trust
as Lucia

On Your Tiptoes
as Nunzia

Rocco Chinnici: May Your Kiss Lie Lightly On My Head
as Caterina Chinnici

Mister Happiness
as Caterina De Simone

Gomorrah
as Patrizia Santoro

Third Contact
as Theresa

Moths
as Sophie

Made in Hollywood
as Self
La Fabbrica delle storie. Follonica 1842-2023
Solo se canti tu - L'irresistibile storia di Gigi D'Alessio
as Madre di Gigi D'Alessio

The Panic
as Belle DeCosta Greene