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Mako was born in Kobe, Japan, the son of noted children's book author and illustrator Taro Yashima. His parents moved to the United States when he was a small child. He joined them there after World War II, in 1949, joining the military in the 1950s. He became a naturalized American citizen in 1956. When Mako first joined his parents in the USA, he studied architecture. During his military service, he discovered his theatrical talent, and trained at the Pasadena Community Playhouse. Mako was married to actress Shizuko Hoshi with whom he had two daughters (both are actresses) and three grandchildren.

Samurai Jack: The Premiere Movie
as Aku (voice)

Rise: Blood Hunter
as Poe

TMNT
as Splinter (voice)

Cages
as Tan

The Slanted Screen
as Himself

Memoirs of a Geisha
as Sakamoto
Maid in Akihabara

Avatar: The Last Airbender
as Iroh (voice)

Super Robot Monkey Team Hyperforce Go!

Duck Dodgers
as Happy Cat (voice)
Lost at Home

Black Sash
as Master Li

Bulletproof Monk
as Mr. Kojima

Cruel Game
as Straw Hat

What's New, Scooby-Doo?
as The Ancient One (voice)

Monk
as Master Zi

Samurai Jack
as Aku (voice)

Pearl Harbor
as Admiral Yamamoto

Rugrats in Paris: The Movie
as Mr. Yamaguchi (voice)

The Secret Adventures of Jules Verne

Conan Unchained: The Making of 'Conan'
as The Wizard (archive footage)

The West Wing
as Dr. Yosh Takahashi

The Accomplice
as Santos

Alegría
as Old Momo

Martial Law
as Master Reng

The Bird People in China
as Shen

Seven Years in Tibet
as Kungo Tsarong

Riot
as Mr. Lee

The Sea Wolf

Sworn to Justice
as Mr. Young

7th Heaven
as Henry Muranaka

Balance of Power
as Todo Matsumoto

JAG
as Ichiro Higashimori

Midnight Man
as Buun Som

Crying Freeman
as Shudo Shimazaki

Platypus Man
as Mr. Loo

Highlander III: The Sorcerer
as Nakano

A Dangerous Place
as Sensei

Red Sun Rising
as Buntoro Iga

Diagnosis: Murder
as Lee Moy

Frasier
as Sam Tanaka

Rising Sun
as Yoshida-san

Walker, Texas Ranger
as Dr. Henry Lee

Kung Fu: The Legend Continues
as Li Sung

RoboCop 3
as Kanemitsu

Sidekicks
as Mr. Lee

Nightingale
as Narrator (voice)

My Samurai

Strawberry Road
as Frank Machida

The Perfect Weapon
as Kim

Pacific Heights
as Toshio Watanabe

Taking Care of Business
as Mr. Sakamoto

Hiroshima: Out of the Ashes
as Sgt. Moritaki

Fatal Mission
as Trang

Murder in Paradise
as Capt. Kilalo

An Unremarkable Life
as Max Chin

The Paradise Club
as Mr. Yamamoto

Paradise
as Kao

The Wash
as Nobu Matsumoto

Tucker: The Man and His Dream
as Jimmy